As a Pitt Men’s Study volunteer, you may have been asked to provide us with a saline oral rinse sample at your most recent visit. This is part of a sub-study that we are asking some of our men to participate in. Oral human papillomavirus (HPV or wart virus) infection has been recently identified as a cause of oropharyngeal cancer. Researchers are aiming to compare the persistence and prevalence of oral HPV infection among HIV infected and uninfected men in the Multicenter AIDS Cohort Study (MACS), of which the Pitt Men’s Study is a part. In addition, researchers are attempting to identify and evaluate biological and behavioral risk factors for oral HPV infection. This research is needed to better understand both who is at risk of HPV-associated oral cancers and the magnitude of these risks. If you are a Pitt Men’s Study volunteer and need more information, contact the clinic at 412-624-2008 or 1-800-987-1963 .